Across TCGA patient cohorts, SSX7 mutation is significantly associated with the RNA expression of many other genes, with 768 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSX7-associated genes across cancer lineages are RNA5SP411, PDE12, and MIR8081. Each is linked with SSX7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSX7-to-partner and partner-to-SSX7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX7→partner) and Y-score (partner→SSX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+2.056	+2.808	<.001	<.001	3	2
UCEC	PDE12 →	+0.511	+2.595	.004	.006	3	2
SKCM	MIR8081 →	+0.398	+2.572	<.001	<.001	3	2
UCEC	ABALON →	+0.651	+3.212	<.001	.009	3	2
SKCM	PRORP →	+0.380	+2.328	.001	.003	3	2
SKCM	AAGAB →	+0.526	+3.070	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 768 associations by consensus.

Exploration

SSX7 survival (RNA) · tumor vs normal (RNA) · all SSX7 data types