Across TCGA patient cohorts, SSX7 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSX7-associated genes across cancer lineages are INPP4B, EGFR_pY1068, and MIG-6. Each is linked with SSX7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSX7-to-partner and partner-to-SSX7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX7→partner) and Y-score (partner→SSX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.309	-3.169	.048	.018	3	2
UCEC	EGFR_pY1068 →	-0.254	-3.169	.036	.018	3	1
UCEC	MIG-6 →	+0.136	+3.331	.004	.005	3	1
UCEC	mTOR_pS2448 →	-0.214	-3.584	.002	.002	3	1
UCEC	PDCD4 →	-0.907	-3.584	<.001	.002	3	1
UCEC	PI3K-p110-a →	-0.172	-2.459	.043	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

SSX7 survival (RNA) · tumor vs normal (RNA) · all SSX7 data types