SSX5

Across TCGA pan-cancer cohorts, SSX5 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SSX5 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher SSX5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SSX5 expression acts as an unfavorable survival marker.

BRCA, LIHC, and COAD are the cancer types where SSX5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.287	0.924	<.001	36	view →
LIHC	OS	Median	All	0.195	0.777	.005	18	view →
COAD	DFS	Median	All	0.223	0.690	.011	12	view →
ACC	DFS	Median	All	0.089	0.666	.017	6	view →
LUAD	OS	Median	All	0.258	0.787	.018	6	view →
SKCM	OS	Median	All	0.468	0.783	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SSX5–BRCA (OS)

Open the BRCA breakdown →