SSX2IP

Across TCGA cell cohorts, SSX2IP mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SSX2IP-associated genes across cancer lineages are UGT2B10, CD1C, and DPPA5. Each is linked with SSX2IP in more than 1 cancer types. Because this analysis shows association rather than direction, both SSX2IP-to-partner and partner-to-SSX2IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B10 grouped by SSX2IP-low versus SSX2IP-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX2IP→partner) and Y-score (partner→SSX2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	UGT2B10 →	+0.049	+5.321	<.001	.005	3	1
CNS	CD1C →	+0.025	+4.981	<.001	.008	3	1
CNS	DPPA5 →	+0.037	+4.981	<.001	.008	3	1
CNS	OR5L1 →	+0.049	+5.754	<.001	.002	3	1
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
OVARY	GPR148 →	+0.054	+4.095	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

UGT2B10 by SSX2IP expression — CNS

Explore this box plot interactively →