SSX1

Across TCGA patient cohorts, SSX1 mutation is significantly associated with the RNA expression of many other genes, with 3,652 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSX1-associated genes across cancer lineages are ENO2, DAPK3, and MIR4445. Each is linked with SSX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSX1-to-partner and partner-to-SSX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ENO2 grouped by SSX1-low versus SSX1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX1→partner) and Y-score (partner→SSX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ENO2 →	+0.995	+2.662	<.001	<.001	3	2
UCEC	DAPK3 →	+0.473	+3.708	.001	<.001	3	2
UCEC	MIR4445 →	+0.146	+4.156	<.001	.004	3	2
UCEC	MYO15B →	-0.765	-3.700	.001	.001	3	2
UCEC	COPS8P1 →	+0.068	+2.064	.001	.003	3	1
UCEC	SRXN1 →	+0.450	+1.819	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,652 associations by consensus.

ENO2 by SSX1 expression — UCEC

Explore this box plot interactively →