SSUH2

Across TCGA patient cohorts, SSUH2 mutation is significantly associated with the RNA expression of many other genes, with 1,614 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSUH2-associated genes across cancer lineages are RNA5SP86, RNU7-11P, and RNU6-789P. Each is linked with SSUH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSUH2-to-partner and partner-to-SSUH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP86 grouped by SSUH2-low versus SSUH2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSUH2→partner) and Y-score (partner→SSUH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNA5SP86 →	+0.457	+5.912	<.001	.002	3	2
LIHC	RNU7-11P →	+0.625	+5.355	<.001	.005	3	2
SKCM	RNU6-789P →	+0.223	+3.159	<.001	.008	3	2
SKCM	ATP6V0E1P1 →	+0.167	+3.118	<.001	.002	3	2
HNSC	LINC01477 →	+0.067	+5.015	.003	.009	3	2
SKCM	RPL32P4 →	+0.357	+3.687	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,614 associations by consensus.

RNA5SP86 by SSUH2 expression — HNSC

Explore this box plot interactively →