SSUH2

Across TCGA patient cohorts, SSUH2 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSUH2-associated genes across cancer lineages are eEF2, p27_pT198, and Rad50. Each is linked with SSUH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSUH2-to-partner and partner-to-SSUH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by SSUH2-low versus SSUH2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSUH2→partner) and Y-score (partner→SSUH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.282	+3.169	.032	.018	3	2
UCEC	p27_pT198 →	+0.081	+1.502	.040	.030	3	2
UCEC	Rad50 →	-0.248	-1.502	.005	.030	3	2
UCEC	TFRC →	+0.509	+2.321	.009	.033	3	2
UCEC	BRCA2 →	-0.115	-1.758	.016	.014	3	2
UCEC	Chk2_pT68 →	-0.139	-2.295	.042	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

eEF2 by SSUH2 expression — UCEC

Explore this box plot interactively →