SSU72

Across TCGA patient cohorts, SSU72 protein abundance is significantly associated with the RNA expression of many other genes, with 11,406 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SSU72-associated genes across cancer lineages are VRK1, SASS6, and AUNIP. Each is linked with SSU72 in more than 5 cancer types. Because this analysis shows association rather than direction, both SSU72-to-partner and partner-to-SSU72 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SSU72 versus VRK1 in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSU72→partner) and Y-score (partner→SSU72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	+0.679	+0.171	<.001	<.001	3	6
LSCC	SASS6 →	+0.621	+0.175	<.001	<.001	3	6
UCEC	AUNIP →	+0.839	+0.217	.003	.004	3	6
LUAD	NUP155 →	+0.654	+0.212	<.001	<.001	3	5
HNSC	CCT4 →	+0.934	+0.195	.006	.002	3	5
LSCC	TTF2 →	+0.567	+0.148	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,406 associations by consensus.

SSU72 vs VRK1 — LSCC

Explore this scatter interactively →