SSTR2

Across TCGA patient cohorts, SSTR2 mutation is significantly associated with the RNA expression of many other genes, with 3,168 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSTR2-associated genes across cancer lineages are RN7SKP145, SAP18, and TEX30. Each is linked with SSTR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SSTR2-to-partner and partner-to-SSTR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP145 grouped by SSTR2-low versus SSTR2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR2→partner) and Y-score (partner→SSTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SKP145 →	+0.099	+7.930	<.001	.008	3	3
UCEC	SAP18 →	+0.300	+3.749	.002	<.001	3	2
UCEC	TEX30 →	+0.671	+2.593	<.001	<.001	3	2
UCEC	RAD17 →	+0.540	+2.459	<.001	<.001	3	2
UCEC	CWC27 →	+0.554	+3.872	<.001	<.001	3	2
UCEC	CENPH →	+0.764	+2.081	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,168 associations by consensus.

RN7SKP145 by SSTR2 expression — LUAD

Explore this box plot interactively →