Across TCGA patient cohorts, SSPOP mutation is significantly associated with the total protein of many other genes, with 129 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SSPOP-associated genes across cancer lineages are ASNS, C-Raf, and PAI-1. Each is linked with SSPOP in more than 5 cancer types. Because this analysis shows association rather than direction, both SSPOP-to-partner and partner-to-SSPOP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSPOP→partner) and Y-score (partner→SSPOP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ASNS →	+0.525	+1.999	<.001	.009	3	6
UCEC	C-Raf →	+0.101	+1.137	.001	.006	3	5
COAD	PAI-1 →	+0.447	+2.339	.004	.002	3	5
STAD	Caveolin-1 →	-0.718	-2.502	.007	.001	3	4
STAD	NF-kB-p65_pS536 →	-0.463	-3.321	.003	.008	3	4
LUSC	G6PD →	+0.303	+2.000	.024	.027	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 129 associations by consensus.

Exploration

SSPOP survival (RNA) · tumor vs normal (RNA) · all SSPOP data types