Across TCGA cell cohorts, SSPOP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,541 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SSPOP-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Purine ribonucleoside triphosphate metabolic process, and Calcium-independent cell-matrix adhesion. Each is linked with SSPOP in more than 13 cancer types. Because this analysis shows association rather than direction, both SSPOP-to-partner and partner-to-SSPOP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSPOP→partner) and Y-score (partner→SSPOP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.142	+1.294	.001	<.001	3	14
BONE	Purine ribonucleoside triphosphate metabolic process →	+0.088	+1.306	<.001	.008	3	11
SOFT_TISSUE	Calcium-independent cell-matrix adhesion →	+0.154	+1.200	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Blood coagulation, intrinsic pathway →	-0.322	-0.847	<.001	.001	3	11
BREAST	Cytoskeleton-dependent intracellular transport →	+0.045	+1.548	<.001	<.001	3	11
OESOPHAGUS	Regulation of macroautophagy →	+0.111	+1.371	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,541 associations by consensus.

Exploration

SSPOP survival (RNA) · tumor vs normal (RNA) · all SSPOP data types