SSPN

Across TCGA cell cohorts, SSPN mutation is significantly associated with the drug of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SSPN-associated genes across cancer lineages are 150412, Ispinesib Mesylate, and GSK1070916. Each is linked with SSPN in more than 1 cancer types. Because this analysis shows association rather than direction, both SSPN-to-partner and partner-to-SSPN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 150412 grouped by SSPN-low versus SSPN-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSPN→partner) and Y-score (partner→SSPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	150412 →	+0.379	+2.777	.024	.038	3	1
LARGE_INTESTINE	Ispinesib Mesylate →	+0.695	+2.652	.033	.045	3	1
LARGE_INTESTINE	GSK1070916 →	+0.821	+2.655	.005	.044	3	1
LARGE_INTESTINE	WZ3105 →	+0.746	+2.652	.031	.045	3	1
LARGE_INTESTINE	PHA-793887 →	+0.902	+2.652	.012	.045	3	1
LARGE_INTESTINE	GSK690693 →	+0.515	+2.652	.043	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

150412 by SSPN expression — LARGE_INTESTINE

Explore this box plot interactively →