SSH1

Across TCGA cell cohorts, SSH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,081 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SSH1-associated GO terms across cancer lineages are Positive regulation of postsynaptic membrane organization, Positive regulation of AMPA glutamate receptor clustering, and Endocytic recycling. Each is linked with SSH1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SSH1-to-partner and partner-to-SSH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of postsynaptic membrane organization grouped by SSH1-low versus SSH1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSH1→partner) and Y-score (partner→SSH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of postsynaptic membrane organization →	+0.270	+1.494	<.001	<.001	3	18
BONE	Positive regulation of AMPA glutamate receptor clustering →	+0.270	+1.494	<.001	<.001	3	18
STOMACH	Endocytic recycling →	+0.064	+1.022	.001	<.001	3	17
SOFT_TISSUE	Regulation of glutamate receptor clustering →	+0.187	+1.450	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.051	+1.270	.001	<.001	3	16
SOFT_TISSUE	Regulation of AMPA glutamate receptor clustering →	+0.187	+1.450	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,081 associations by consensus.

Positive regulation of postsynaptic membrane organization by SSH1 expression — BONE

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