SSC5D

Across TCGA pan-cancer cohorts, SSC5D mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SSC5D data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SSC5D mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SSC5D expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, LUAD, and COAD are the cancer types where SSC5D mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	II,III,IV	0.938	0.615	.002	30	view →
LUAD	OS	Tertile	All	0.887	1.000	.009	26	view →
COAD	DFS	Median	All	0.885	1.000	.019	18	view →
LSCC	DFS	Median	II,III,IV	0.828	1.000	.003	14	view →
GBM	OS	Median	All	0.270	0.503	.015	12	view →
CCRCC	DFS	Median	III,IV	0.145	0.774	.016	8	view →
HNSC	DFS	Median	III,IV	0.869	0.724	.021	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SSC5D–PDAC (DFS)

Open the PDAC breakdown →