SSC4D

Across TCGA cell cohorts, SSC4D RNA expression is significantly associated with the go_rna of many other GO terms, with 2,074 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SSC4D-associated GO terms across cancer lineages are Purine ribonucleotide biosynthetic process, Ribonucleotide biosynthetic process, and Purine nucleoside triphosphate biosynthetic process. Each is linked with SSC4D in more than 8 cancer types. Because this analysis shows association rather than direction, both SSC4D-to-partner and partner-to-SSC4D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine ribonucleotide biosynthetic process grouped by SSC4D-low versus SSC4D-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSC4D→partner) and Y-score (partner→SSC4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Purine ribonucleotide biosynthetic process →	+0.063	+0.437	<.001	<.001	3	9
OVARY	Ribonucleotide biosynthetic process →	+0.059	+1.351	<.001	<.001	3	9
BREAST	Purine nucleoside triphosphate biosynthetic process →	+0.069	+0.675	.002	.005	3	8
BREAST	Purine ribonucleoside triphosphate biosynthetic process →	+0.069	+0.675	.002	.005	3	8
BREAST	Electron transport chain →	+0.075	+0.775	<.001	.001	3	8
LUNG_NSCLC_LUAD	Purine nucleotide biosynthetic process →	+0.049	+0.556	.005	.008	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,074 associations by consensus.

Purine ribonucleotide biosynthetic process by SSC4D expression — BLOOD_Leukemia

Explore this box plot interactively →