SS18

Across TCGA patient cohorts, SS18 protein abundance is significantly associated with the RNA expression of many other genes, with 11,002 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SS18-associated genes across cancer lineages are TAF4B, KIAA1328, and KATNAL2. Each is linked with SS18 in more than 5 cancer types. Because this analysis shows association rather than direction, both SS18-to-partner and partner-to-SS18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SS18 versus TAF4B in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SS18→partner) and Y-score (partner→SS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TAF4B →	+0.749	+0.238	.001	.002	3	6
LSCC	KIAA1328 →	+0.449	+0.251	<.001	<.001	3	5
LSCC	KATNAL2 →	+0.841	+0.297	<.001	<.001	3	5
GBM	TREM1 →	-1.264	-0.276	.001	.001	3	5
HNSC	FPR1 →	-1.180	-0.443	.001	<.001	3	5
HNSC	LRP6 →	+0.617	+0.232	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,002 associations by consensus.

SS18 vs TAF4B — BRCA

Explore this scatter interactively →