SRSF8

Across TCGA patient cohorts, SRSF8 RNA expression is significantly associated with the RNA expression of many other genes, with 19,721 significant associations in total. UVM shows the largest number of these associations.

The most reproducible SRSF8-associated genes across cancer lineages are ALKBH8, CWF19L2, and JRKL. Each is linked with SRSF8 in more than 33 cancer types. Because this analysis shows association rather than direction, both SRSF8-to-partner and partner-to-SRSF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRSF8 versus ALKBH8 in UVM, with a Pearson correlation of 0.91.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF8→partner) and Y-score (partner→SRSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	ALKBH8 →	+1.220	+1.081	<.001	<.001	3	34
UVM	CWF19L2 →	+1.312	+1.055	<.001	<.001	3	34
DLBC	JRKL →	+1.727	+0.695	<.001	<.001	3	34
UVM	FAM76B →	+1.330	+0.981	<.001	<.001	3	34
UVM	MRE11 →	+1.311	+1.126	<.001	<.001	3	34
UVM	MTMR2 →	+1.057	+1.066	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,721 associations by consensus.

SRSF8 vs ALKBH8 — UVM

Explore this scatter interactively →