SRSF6

Across TCGA patient cohorts, SRSF6 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,380 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SRSF6-associated proteins across cancer lineages are ADNP, LSP1, and CSTF1. Each is linked with SRSF6 in more than 6 cancer types. Because this analysis shows association rather than direction, both SRSF6-to-partner and partner-to-SRSF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRSF6 versus ADNP in GBM, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF6→partner) and Y-score (partner→SRSF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ADNP →	+0.445	+0.491	<.001	<.001	3	7
GBM	LSP1 →	-0.542	-0.405	.002	<.001	3	7
GBM	CSTF1 →	+0.313	+0.448	<.001	<.001	3	6
GBM	CSTF3 →	+0.323	+0.528	<.001	<.001	3	6
LSCC	DDX27 →	+0.463	+0.498	<.001	<.001	3	6
GBM	DHX9 →	+0.234	+0.308	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,380 associations by consensus.

SRSF6 vs ADNP — GBM

Explore this scatter interactively →