SRSF3

Across TCGA patient cohorts, SRSF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,714 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRSF3-associated proteins across cancer lineages are MCM4, RIF1, and SIN3A. Each is linked with SRSF3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SRSF3-to-partner and partner-to-SRSF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRSF3 versus MCM4 in GBM, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF3→partner) and Y-score (partner→SRSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCM4 →	+0.838	+0.473	<.001	<.001	3	8
LSCC	RIF1 →	+0.483	+0.514	<.001	<.001	3	7
GBM	SIN3A →	+0.241	+0.305	<.001	<.001	3	7
LSCC	SUPT6H →	+0.262	+0.490	<.001	<.001	3	7
GBM	MCM3 →	+0.866	+0.449	<.001	<.001	3	7
GBM	MCM5 →	+0.828	+0.445	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,714 associations by consensus.

SRSF3 vs MCM4 — GBM

Explore this scatter interactively →