SRSF12

Across TCGA cell cohorts, SRSF12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,992 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SRSF12-associated GO terms across cancer lineages are Renal vesicle formation, Metanephric renal vesicle formation, and RNA splicing, via transesterification reactions. Each is linked with SRSF12 in more than 12 cancer types. Because this analysis shows association rather than direction, both SRSF12-to-partner and partner-to-SRSF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal vesicle formation grouped by SRSF12-low versus SRSF12-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF12→partner) and Y-score (partner→SRSF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Renal vesicle formation →	+1.449	+1.013	<.001	.004	3	13
OESOPHAGUS	Metanephric renal vesicle formation →	+1.449	+1.013	<.001	.004	3	13
LUNG_SCLC	RNA splicing, via transesterification reactions →	+0.069	+1.815	<.001	<.001	3	13
BONE	Positive regulation of monoatomic ion transport →	-0.113	-1.658	.003	.001	3	13
LUNG_SCLC	Regulation of DNA repair →	+0.074	+1.945	<.001	<.001	3	13
LIVER	Regulation of potassium ion transmembrane transport →	-0.209	-2.105	.003	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,992 associations by consensus.

Renal vesicle formation by SRSF12 expression — OESOPHAGUS

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