SRSF11

Across TCGA patient cohorts, SRSF11 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,417 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SRSF11-associated proteins across cancer lineages are LRRC40, EFTUD2, and MFAP1. Each is linked with SRSF11 in more than 5 cancer types. Because this analysis shows association rather than direction, both SRSF11-to-partner and partner-to-SRSF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRSF11 versus LRRC40 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF11→partner) and Y-score (partner→SRSF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LRRC40 →	+0.303	+0.411	.001	.001	3	6
GBM	EFTUD2 →	+0.235	+0.432	.001	<.001	2	6
GBM	MFAP1 →	+0.290	+0.345	<.001	<.001	3	5
GBM	XAB2 →	+0.206	+0.404	.001	.002	3	5
CCRCC	SAR1B →	-0.344	-0.263	<.001	<.001	3	5
GBM	SF3A3 →	+0.257	+0.499	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,417 associations by consensus.

SRSF11 vs LRRC40 — GBM

Explore this scatter interactively →