SRSF11

Across TCGA patient cohorts, SRSF11 protein abundance is significantly associated with the RNA expression of many other genes, with 17,223 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRSF11-associated genes across cancer lineages are USP21, CHTOP, and POLR1C. Each is linked with SRSF11 in more than 6 cancer types. Because this analysis shows association rather than direction, both SRSF11-to-partner and partner-to-SRSF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRSF11 versus USP21 in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF11→partner) and Y-score (partner→SRSF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	USP21 →	+0.621	+0.210	<.001	<.001	3	7
LUAD	CHTOP →	+0.494	+0.176	<.001	<.001	3	7
LSCC	POLR1C →	+0.814	+0.258	<.001	<.001	3	7
LSCC	DNA2 →	+0.799	+0.257	<.001	<.001	3	6
LSCC	TARS2 →	+0.562	+0.218	<.001	<.001	3	6
LSCC	CCDC138 →	+0.737	+0.238	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,223 associations by consensus.

SRSF11 vs USP21 — UCEC

Explore this scatter interactively →