SRRD

Across TCGA patient cohorts, SRRD RNA expression is significantly associated with the protein abundance of many other proteins, with 14,367 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRRD-associated proteins across cancer lineages are MICAL3, MIF, and KIAA1671. Each is linked with SRRD in more than 5 cancer types. Because this analysis shows association rather than direction, both SRRD-to-partner and partner-to-SRRD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRRD versus MICAL3 in GBM, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRRD→partner) and Y-score (partner→SRRD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MICAL3 →	+0.528	+0.433	<.001	<.001	3	5
BRCA	MIF →	+0.408	+0.498	<.001	<.001	2	6
BRCA	KIAA1671 →	+0.313	+0.343	<.001	<.001	3	5
LSCC	KIAA1671_S1366 →	+0.562	+0.334	.002	.005	3	5
GBM	ATXN10 →	+0.349	+0.375	<.001	<.001	3	5
BRCA	PITPNB →	+0.380	+0.498	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,367 associations by consensus.

SRRD vs MICAL3 — GBM

Explore this scatter interactively →