SRPRB

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SRPRB RNA expression is significantly associated with the protein abundance of many other proteins, with 14,245 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRPRB-associated proteins across cancer lineages are EIF4G1, NOP16, and DHX36. Each is linked with SRPRB in more than 6 cancer types. Because this analysis shows association rather than direction, both SRPRB-to-partner and partner-to-SRPRB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRPRB versus EIF4G1 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRPRB→partner) and Y-score (partner→SRPRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCEIF4G1 →+0.290+0.481<.001<.00137
GBMNOP16 →+0.405+0.349<.001<.00136
LSCCDHX36 →+0.400+0.548<.001<.00136
LSCCMYBBP1A_S1267 →+0.491+0.392<.001<.00135
UCECNAA10 →+0.320+0.653<.001<.00135
LSCCNMD3 →+0.296+0.600<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,245 associations by consensus.

SRPRB vs EIF4G1 — LSCC

Per-sample scatter of SRPRB vs EIF4G1 in LSCC (Pearson r = 0.54).

Explore this scatter interactively →

Exploration