Across TCGA patient cohorts, SRPK3 protein abundance is significantly associated with the protein abundance of many other proteins, with 241 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SRPK3-associated proteins across cancer lineages are OVCA2, PMS1, and PREX1_S1200. Each is linked with SRPK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SRPK3-to-partner and partner-to-SRPK3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRPK3→partner) and Y-score (partner→SRPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OVCA2 →	+0.357	+1.351	.002	<.001	3	1
LUAD	PMS1 →	+0.530	+1.434	.001	.001	3	1
LUAD	PREX1_S1200 →	+0.440	+1.351	<.001	<.001	3	1
LUAD	PRX_S1082 →	+2.124	+1.437	<.001	<.001	3	1
LUAD	DIP2B_S201 →	+0.581	+1.172	.002	.002	3	1
LUAD	GCSH →	+0.493	+1.557	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 241 associations by consensus.

Exploration

SRPK3 survival (RNA) · tumor vs normal (RNA) · all SRPK3 data types