Across TCGA cell cohorts, SRPK3 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SRPK3-associated genes across cancer lineages are CARTPT, LIPN, and PRR20C. Each is linked with SRPK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SRPK3-to-partner and partner-to-SRPK3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRPK3→partner) and Y-score (partner→SRPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CARTPT →	+0.017	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	LIPN →	+0.039	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	PRR20C →	+0.056	+4.371	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR10G2 →	+0.026	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	TEX49 →	+0.114	+4.544	<.001	.003	3	1
SKIN	KCNA6 →	+0.011	+5.217	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

SRPK3 survival (RNA) · tumor vs normal (RNA) · all SRPK3 data types