SRPK1

Across TCGA patient cohorts, SRPK1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,451 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRPK1-associated genes across cancer lineages are CDCA7, ABCA6, and POC1A. Each is linked with SRPK1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SRPK1-to-partner and partner-to-SRPK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRPK1 versus CDCA7 in BRCA, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRPK1→partner) and Y-score (partner→SRPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDCA7 →	+1.267	+0.414	<.001	<.001	3	8
GBM	ABCA6 →	-0.904	-0.233	<.001	<.001	3	8
UCEC	POC1A →	+1.154	+0.261	<.001	.001	3	8
UCEC	GMNN →	+0.993	+0.369	<.001	<.001	3	8
UCEC	PPIL1 →	+1.032	+0.388	<.001	<.001	3	8
UCEC	JPT1 →	+1.290	+0.363	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,451 associations by consensus.

SRPK1 vs CDCA7 — BRCA

Explore this scatter interactively →