SRP72

Across TCGA cell cohorts, SRP72 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,480 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SRP72-associated GO terms across cancer lineages are 'de novo' AMP biosynthetic process, IMP biosynthetic process, and 'de novo' IMP biosynthetic process. Each is linked with SRP72 in more than 15 cancer types. Because this analysis shows association rather than direction, both SRP72-to-partner and partner-to-SRP72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' AMP biosynthetic process grouped by SRP72-low versus SRP72-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRP72→partner) and Y-score (partner→SRP72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	'de novo' AMP biosynthetic process →	+0.137	+0.635	<.001	<.001	3	16
BLOOD_Myeloma	IMP biosynthetic process →	+0.174	+0.795	<.001	<.001	3	13
BLOOD_Myeloma	'de novo' IMP biosynthetic process →	+0.148	+0.829	.002	<.001	3	13
LARGE_INTESTINE	Ribosomal large subunit export from nucleus →	+0.113	+0.925	<.001	<.001	3	13
BLOOD_Lymphoma	GMP biosynthetic process →	+0.106	+0.787	<.001	.001	3	13
BLOOD_Lymphoma	Meiotic metaphase chromosome alignment →	+0.082	+0.563	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,480 associations by consensus.

'de novo' AMP biosynthetic process by SRP72 expression — OVARY

Explore this box plot interactively →