SRP68P1

Across TCGA pan-cancer cohorts, SRP68P1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of SRP68P1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where SRP68P1 RNA is repressed in tumor relative to normal tissue. In most cancer types SRP68P1 is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

BRCA, LUAD, and UCEC are the cancer types where SRP68P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SRP68P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	IV	−0.725	.004	2	view →
LUAD	All	II,III,IV	−0.257	.016	2	view →
UCEC	All	All	−0.194	.036	2	view →
COAD	Female	All	−0.179	.017	2	view →
KICH	All	All	+0.245	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

SRP68P1–BRCA

Open the BRCA breakdown →