Q-omics provides the consensus-scored SRP68P1 profile across patient tissues and cancer cell-line models. SRP68P1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in CHOL. Among the 18 cancer types available for tumor–normal comparison, SRP68P1 is differentially expressed in 5, with the highest sampling consensus in BRCA. Additionally, SRP68P1 RNA expression shows 13,010 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight CHOL, BRCA, and THYM as cancer lineages where SRP68P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SRP68P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SRP68P1 survival associations across molecular data types. SRP68P1 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SRP68P1 RNA expression–survival associations across cancer types. High SRP68P1 expression shows unfavorable associations in CHOL, COAD, ESCA, ACC and THCA, but favorable associations in KIRP. The CHOL Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .008). Together, the overview and detailed table identify CHOL as the clearest survival context for SRP68P1 RNA expression.
This table summarizes SRP68P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for SRP68P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SRP68P1 shows lower tumor expression in BRCA, LUAD, UCEC and COAD and higher tumor expression in KICH. The BRCA box plot shows higher SRP68P1 RNA expression in normal versus tumor tissue (log2 FC = −0.725, t-test p = .004).
This table shows molecular features associated with SRP68P1 in patient tissues and cancer cell lines. In patient samples, SRP68P1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
