SRP68

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SRP68 protein abundance is significantly associated with the RNA expression of many other genes, with 16,749 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRP68-associated genes across cancer lineages are CSDC2, GPRASP1, and MYLK. Each is linked with SRP68 in more than 7 cancer types. Because this analysis shows association rather than direction, both SRP68-to-partner and partner-to-SRP68 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRP68 versus CSDC2 in CCRCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRP68→partner) and Y-score (partner→SRP68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCCSDC2 →-1.674-0.268<.001<.00137
OVGPRASP1 →-0.799-0.211.003.00528
COADMYLK →-1.215-0.164<.001.00137
HNSCHDAC5 →-0.647-0.190<.001<.00136
LSCCZC3H13 →-0.569-0.323<.001<.00136
HNSCRBMS3 →-0.653-0.192<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,749 associations by consensus.

SRP68 vs CSDC2 — CCRCC

Per-sample scatter of SRP68 vs CSDC2 in CCRCC (Pearson r = -0.40).

Explore this scatter interactively →

Exploration