SRP14

Across TCGA patient cohorts, SRP14 protein abundance is significantly associated with the RNA expression of many other genes, with 9,880 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SRP14-associated genes across cancer lineages are FGR, S100A8, and BEST1. Each is linked with SRP14 in more than 7 cancer types. Because this analysis shows association rather than direction, both SRP14-to-partner and partner-to-SRP14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRP14 versus FGR in OV, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRP14→partner) and Y-score (partner→SRP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FGR →	-0.739	-0.469	.005	.001	3	8
BRCA	S100A8 →	-2.344	-0.328	.001	<.001	3	7
GBM	BEST1 →	-0.799	-0.426	<.001	<.001	3	7
CCRCC	CXCL8 →	-1.950	-0.194	<.001	<.001	3	7
GBM	PELATON →	-0.644	-0.385	<.001	<.001	3	7
UCEC	CXCR2 →	-1.000	-0.325	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,880 associations by consensus.

SRP14 vs FGR — OV

Explore this scatter interactively →