SRGAP3-AS4

Across TCGA pan-cancer cohorts, SRGAP3-AS4 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated SRGAP3-AS4 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher SRGAP3-AS4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated SRGAP3-AS4 expression acts as an unfavorable survival marker, although some lineages such as BLCA and MESO show a favorable association.

BLCA, MESO, and THYM are the cancer types where SRGAP3-AS4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.541	0.339	<.001	93	view →
MESO	OS	Median	All	0.540	0.307	.001	27	view →
THYM	OS	Tertile	II,III,IV	0.664	1.000	.022	19	view →
ESCA	DFS	Median	II,III,IV	0.417	0.221	.014	19	view →
COAD	DFS	Tertile	II,III,IV	0.849	0.606	.014	18	view →
PAAD	DFS	Tertile	All	0.533	0.234	.009	17	view →
OV	OS	Median	IV	0.499	0.731	.015	16	view →
LAML	DFS	Tertile	All	0.616	0.294	.008	12	view →
LUAD	OS	Quartile	All	0.870	0.783	.011	11	view →
ACC	OS	Tertile	All	0.933	0.731	.008	10	view →
SKCM	DFS	Tertile	IV	0.016	0.541	.008	9	view →
THCA	DFS	Median	IV	0.480	0.783	.018	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

SRGAP3-AS4–BLCA (OS)

Open the BLCA breakdown →