SRGAP3-AS2

Across TCGA pan-cancer cohorts, SRGAP3-AS2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SRGAP3-AS2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SRGAP3-AS2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated SRGAP3-AS2 expression acts as an unfavorable survival marker, although some lineages such as ACC and LAML show a favorable association.

ACC, THCA, and LIHC are the cancer types where SRGAP3-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.807	0.458	<.001	123	view →
THCA	DFS	Tertile	III,IV	0.487	0.772	<.001	86	view →
LIHC	OS	Quartile	All	0.651	0.810	<.001	86	view →
LAML	DFS	Median	All	0.531	0.230	<.001	38	view →
UVM	OS	Tertile	III,IV	0.194	0.697	.008	36	view →
OV	DFS	Quartile	II,III,IV	0.332	0.433	.018	32	view →
CHOL	DFS	Quartile	All	0.167	0.692	.002	31	view →
BRCA	DFS	Quartile	All	0.930	0.885	.012	31	view →
UCEC	OS	Median	All	0.956	0.896	.004	24	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
LGG	DFS	Tertile	All	0.625	0.765	<.001	17	view →
STAD	OS	Median	IV	0.642	0.194	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SRGAP3-AS2–ACC (OS)

Open the ACC breakdown →