SRGAP2C

Across TCGA cell cohorts, SRGAP2C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,961 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SRGAP2C-associated GO terms across cancer lineages are Positive regulation of neuron migration, Positive regulation of organelle assembly, and Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration. Each is linked with SRGAP2C in more than 12 cancer types. Because this analysis shows association rather than direction, both SRGAP2C-to-partner and partner-to-SRGAP2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of neuron migration grouped by SRGAP2C-low versus SRGAP2C-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRGAP2C→partner) and Y-score (partner→SRGAP2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of neuron migration →	+0.097	+1.428	<.001	.006	3	13
LUNG_NSCLC_LUSC	Positive regulation of organelle assembly →	+0.080	+1.544	<.001	<.001	3	13
OVARY	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.140	+0.985	<.001	<.001	3	13
BREAST	Positive regulation of cell cycle →	+0.061	+0.882	<.001	<.001	3	12
SOFT_TISSUE	Regulation of protein sumoylation →	+0.106	+0.853	.001	<.001	3	12
LUNG_NSCLC_LUSC	Centrosome cycle →	+0.073	+1.195	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,961 associations by consensus.

Positive regulation of neuron migration by SRGAP2C expression — BLOOD_Myeloma

Explore this box plot interactively →