Across TCGA patient cohorts, SRGAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,788 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SRGAP1-associated genes across cancer lineages are RPL36AP41, DHDH, and GPRC5A. Each is linked with SRGAP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SRGAP1-to-partner and partner-to-SRGAP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRGAP1→partner) and Y-score (partner→SRGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL36AP41 →	+0.928	+0.426	<.001	<.001	3	7
CCRCC	DHDH →	-1.227	-0.187	<.001	.007	3	4
CCRCC	GPRC5A →	+1.272	+0.272	<.001	<.001	3	4
BRCA	HLA-F →	-1.004	-0.341	.002	.004	3	4
BRCA	HLA-B →	-0.875	-0.354	.002	.002	3	4
UCEC	SCEL →	+1.443	+0.280	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,788 associations by consensus.

Exploration

SRGAP1 survival (RNA) · tumor vs normal (RNA) · all SRGAP1 data types