SREK1IP1P2

Across TCGA patient cohorts, SREK1IP1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,568 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SREK1IP1P2-associated GO terms across cancer lineages are Protein insertion into mitochondrial inner membrane, Positive regulation of DNA repair, and Positive regulation of sister chromatid cohesion. Each is linked with SREK1IP1P2 in more than 15 cancer types. Because this analysis shows association rather than direction, both SREK1IP1P2-to-partner and partner-to-SREK1IP1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into mitochondrial inner membrane grouped by SREK1IP1P2-low versus SREK1IP1P2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SREK1IP1P2→partner) and Y-score (partner→SREK1IP1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein insertion into mitochondrial inner membrane →	+0.065	+0.385	.001	<.001	3	16
STAD	Positive regulation of DNA repair →	+0.047	+0.202	<.001	<.001	3	14
STAD	Positive regulation of sister chromatid cohesion →	+0.052	+0.195	<.001	<.001	3	14
STAD	Positive regulation of signal transduction by p53 class mediator →	+0.044	+0.152	<.001	<.001	3	14
STAD	Regulation of Arp2/3 complex-mediated actin nucleation →	+0.050	+0.207	<.001	<.001	3	13
STAD	Regulation of double-strand break repair →	+0.047	+0.171	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,568 associations by consensus.

Protein insertion into mitochondrial inner membrane by SREK1IP1P2 expression — ESCA

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