SREK1IP1P2

Across TCGA pan-cancer cohorts, SREK1IP1P2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated SREK1IP1P2 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SREK1IP1P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SREK1IP1P2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and STAD show a favorable association.

COAD, LIHC, and KIRC are the cancer types where SREK1IP1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.399	0.669	<.001	78	view →
LIHC	DFS	Tertile	All	0.185	0.334	.001	58	view →
KIRC	DFS	Tertile	All	0.536	0.697	.002	38	view →
OV	OS	Quartile	All	0.773	0.895	.002	36	view →
HNSC	OS	Quartile	IV	0.834	0.670	.002	29	view →
THCA	OS	Tertile	IV	0.368	0.871	<.001	27	view →
STAD	DFS	Tertile	IV	0.594	0.159	.019	16	view →
ESCA	DFS	Tertile	All	0.243	0.470	.009	16	view →
DLBC	OS	Tertile	III,IV	0.650	1.000	.009	13	view →
PAAD	OS	Tertile	III,IV	0.723	1.000	.045	12	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	12	view →
READ	DFS	Tertile	IV	0.676	0.623	.037	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

SREK1IP1P2–COAD (OS)

Open the COAD breakdown →