SRD5A3

Across TCGA patient cohorts, SRD5A3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,571 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SRD5A3-associated genes across cancer lineages are SRD5A3-AS1, TTLL12, and DUSP26. Each is linked with SRD5A3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SRD5A3-to-partner and partner-to-SRD5A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRD5A3 versus SRD5A3-AS1 in UCEC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRD5A3→partner) and Y-score (partner→SRD5A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SRD5A3-AS1 →	+0.839	+0.828	<.001	<.001	3	5
OV	TTLL12 →	+0.730	+0.755	.001	.002	3	3
HNSC	DUSP26 →	-1.041	-0.476	.001	.001	3	3
CCRCC	SCHIP1 →	-0.352	-0.570	.003	<.001	3	3
HNSC	MAMDC2 →	-0.713	-0.456	.002	.002	3	3
HNSC	LINC00702 →	-0.786	-0.443	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,571 associations by consensus.

SRD5A3 vs SRD5A3-AS1 — UCEC

Explore this scatter interactively →