Across TCGA patient cohorts, SRARP mutation is significantly associated with the RNA expression of many other genes, with 90 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SRARP-associated genes across cancer lineages are RNA5SP252, LINC01078, and TEX50. Each is linked with SRARP in more than 1 cancer types. Because this analysis shows association rather than direction, both SRARP-to-partner and partner-to-SRARP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRARP→partner) and Y-score (partner→SRARP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNA5SP252 →	+0.343	+5.736	<.001	.003	3	2
HNSC	LINC01078 →	+0.119	+5.368	<.001	.005	3	2
HNSC	TEX50 →	+0.115	+5.736	<.001	.003	3	2
UCEC	RNU6-1228P →	+0.353	+5.464	<.001	.001	3	2
SKCM	RNVU1-18 →	+0.262	+5.159	<.001	.007	3	2
UCEC	SNRPGP17 →	+0.406	+3.879	.007	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 90 associations by consensus.

Exploration

SRARP survival (RNA) · tumor vs normal (RNA) · all SRARP data types