SQLE

Across TCGA patient cohorts, SQLE RNA expression is significantly associated with the RNA expression of many other genes, with 19,381 significant associations in total. THYM shows the largest number of these associations.

The most reproducible SQLE-associated genes across cancer lineages are PPAT, DERL1, and NUP58. Each is linked with SQLE in more than 33 cancer types. Because this analysis shows association rather than direction, both SQLE-to-partner and partner-to-SQLE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SQLE versus PPAT in ACC, with a Pearson correlation of 0.53.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SQLE→partner) and Y-score (partner→SQLE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	PPAT →	+1.121	+2.694	<.001	<.001	3	34
UVM	DERL1 →	+1.416	+1.738	<.001	<.001	3	34
DLBC	NUP58 →	+1.196	+1.074	<.001	<.001	3	34
UVM	UTP23 →	+1.558	+1.619	<.001	<.001	3	34
UVM	OTUD6B →	+1.455	+1.436	<.001	<.001	3	34
UVM	DPY19L4 →	+1.430	+1.582	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,381 associations by consensus.

SQLE vs PPAT — ACC

Explore this scatter interactively →