SPTY2D1

Across TCGA patient cohorts, SPTY2D1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,947 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SPTY2D1-associated genes across cancer lineages are ABCA8, PLSCR4, and KLF12. Each is linked with SPTY2D1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPTY2D1-to-partner and partner-to-SPTY2D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPTY2D1 versus ABCA8 in LSCC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTY2D1→partner) and Y-score (partner→SPTY2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ABCA8 →	-0.784	-0.234	<.001	.005	3	5
CCRCC	PLSCR4 →	-0.729	-0.295	<.001	<.001	3	4
HNSC	KLF12 →	-0.748	-0.368	<.001	<.001	3	4
HNSC	RBMS3 →	-0.576	-0.308	<.001	<.001	3	4
HNSC	ANKAR →	-0.559	-0.353	<.001	<.001	3	4
HNSC	PLCL2 →	-0.617	-0.251	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,947 associations by consensus.

SPTY2D1 vs ABCA8 — LSCC

Explore this scatter interactively →