Across TCGA patient cohorts, SPTSSB RNA expression is significantly associated with the protein abundance of many other proteins, with 9,730 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPTSSB-associated proteins across cancer lineages are KRT19, KRT8, and PPL. Each is linked with SPTSSB in more than 5 cancer types. Because this analysis shows association rather than direction, both SPTSSB-to-partner and partner-to-SPTSSB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTSSB→partner) and Y-score (partner→SPTSSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KRT19 →	+0.848	+0.893	<.001	<.001	3	6
BRCA	KRT8 →	+0.656	+1.689	.001	.002	3	6
UCEC	PPL →	+0.818	+1.518	<.001	<.001	3	5
LUAD	RAB27B →	+0.832	+1.077	<.001	.001	3	4
HNSC	PLS1 →	+0.610	+1.168	<.001	<.001	3	4
LUAD	MYO5B →	+0.519	+1.244	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,730 associations by consensus.

Exploration

SPTSSB survival (RNA) · tumor vs normal (RNA) · all SPTSSB data types