SPTLC1P2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPTLC1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,284 significant associations in total. OV shows the largest number of these associations.

The most reproducible SPTLC1P2-associated GO terms across cancer lineages are Negative regulation of telomere maintenance, Protein retention in Golgi apparatus, and Negative regulation of telomere capping. Each is linked with SPTLC1P2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SPTLC1P2-to-partner and partner-to-SPTLC1P2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTLC1P2→partner) and Y-score (partner→SPTLC1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPNegative regulation of telomere maintenance →+0.024+0.108.001<.001310
ESCAProtein retention in Golgi apparatus →+0.052+0.261<.001.00139
SARCNegative regulation of telomere capping →+0.036+0.130<.001.00229
KIRPNegative regulation of telomere maintenance via telomere lengthening →+0.021+0.084.002<.00129
ACCRhythmic process →+0.030+0.180.001<.00138
UCECVesicle cargo loading →+0.035+0.107<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,284 associations by consensus.

Exploration