Across TCGA patient cohorts, SPTAN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,958 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPTAN1-associated proteins across cancer lineages are PDIA4, PDIA6, and HSP90B1. Each is linked with SPTAN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPTAN1-to-partner and partner-to-SPTAN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTAN1→partner) and Y-score (partner→SPTAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PDIA4 →	-0.581	-0.564	<.001	<.001	3	5
GBM	PDIA6 →	-0.427	-0.492	<.001	<.001	3	5
CCRCC	HSP90B1 →	-0.354	-0.331	<.001	.001	3	5
UCEC	LMAN1 →	-0.414	-0.546	.002	.002	3	5
GBM	PRDX4 →	-0.433	-0.448	<.001	<.001	3	5
LSCC	FUBP3 →	+0.204	+0.339	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,958 associations by consensus.

Exploration

SPTAN1 survival (RNA) · tumor vs normal (RNA) · all SPTAN1 data types