SPTA1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPTA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,116 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPTA1-associated GO terms across cancer lineages are Regulation of cysteine-type endopeptidase activity, Cortical actin cytoskeleton organization, and Regulation of stress-activated protein kinase signaling cascade. Each is linked with SPTA1 in more than 24 cancer types. Because this analysis shows association rather than direction, both SPTA1-to-partner and partner-to-SPTA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTA1→partner) and Y-score (partner→SPTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRegulation of cysteine-type endopeptidase activity →+0.063+0.120<.001<.001325
STADCortical actin cytoskeleton organization →+0.084+0.118<.001<.001325
STADRegulation of stress-activated protein kinase signaling cascade →+0.062+0.116<.001<.001324
STADPositive regulation of B cell activation →+0.065+0.117<.001<.001324
STADRegulation of cell-substrate adhesion →+0.071+0.104<.001<.001324
STADStress-activated protein kinase signaling cascade →+0.064+0.112<.001<.001324
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,116 associations by consensus.

Exploration