SPSB2

Across TCGA patient cohorts, SPSB2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,939 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPSB2-associated genes across cancer lineages are FBP1, RN7SKP91, and LINC02773. Each is linked with SPSB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPSB2-to-partner and partner-to-SPSB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPSB2 versus FBP1 in HNSC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPSB2→partner) and Y-score (partner→SPSB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FBP1 →	-1.437	-0.774	.001	.001	3	2
UCEC	RN7SKP91 →	-1.725	-0.786	<.001	<.001	3	2
HNSC	LINC02773 →	-0.480	-0.913	<.001	.002	3	2
CCRCC	NR4A3 →	-1.907	-1.212	.001	.001	3	2
UCEC	RN7SKP87 →	-1.293	-0.817	.005	<.001	3	2
UCEC	FTH1P16 →	-1.385	-0.861	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,939 associations by consensus.

SPSB2 vs FBP1 — HNSC

Explore this scatter interactively →