SPSB2

Across TCGA cell cohorts, SPSB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,568 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SPSB2-associated GO terms across cancer lineages are Radial spoke assembly, Canonical NF-kappaB signal transduction, and Chylomicron assembly. Each is linked with SPSB2 in more than 11 cancer types. Because this analysis shows association rather than direction, both SPSB2-to-partner and partner-to-SPSB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Radial spoke assembly grouped by SPSB2-low versus SPSB2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPSB2→partner) and Y-score (partner→SPSB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Radial spoke assembly →	+1.348	+0.834	<.001	.008	3	12
LARGE_INTESTINE	Canonical NF-kappaB signal transduction →	+0.058	+0.651	.005	.001	3	8
BREAST	Chylomicron assembly →	+0.153	+0.510	<.001	.004	2	8
SOFT_TISSUE	Fatty acid beta-oxidation using acyl-CoA dehydrogenase →	+0.088	+1.037	<.001	<.001	3	6
BONE	Endosome organization →	+0.036	+0.578	.008	.009	3	6
LARGE_INTESTINE	Regulation of pattern recognition receptor signaling pathway →	+0.041	+0.714	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,568 associations by consensus.

Radial spoke assembly by SPSB2 expression — URINARY_TRACT

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