SPRR4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPRR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,010 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPRR4-associated GO terms across cancer lineages are Positive regulation of epidermis development, Ephrin receptor signaling pathway, and Intermediate filament-based process. Each is linked with SPRR4 in more than 9 cancer types. Because this analysis shows association rather than direction, both SPRR4-to-partner and partner-to-SPRR4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR4→partner) and Y-score (partner→SPRR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAPositive regulation of epidermis development →+0.065+1.864<.001<.001310
ESCAEphrin receptor signaling pathway →+0.056+2.292<.001<.00139
ESCAIntermediate filament-based process →+0.059+1.427<.001<.00139
ESCAEpidermal cell differentiation →+0.072+2.078<.001<.00139
ESCAPeptide cross-linking →+0.155+2.377<.001<.00139
ESCASkin epidermis development →+0.055+2.001<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,010 associations by consensus.

Exploration