SPRR2G

Across TCGA cell cohorts, SPRR2G RNA expression is significantly associated with the RNA expression of many other genes, with 1,497 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible SPRR2G-associated genes across cancer lineages are PGLYRP3, SPRR4, and LCE3D. Each is linked with SPRR2G in more than 8 cancer types. Because this analysis shows association rather than direction, both SPRR2G-to-partner and partner-to-SPRR2G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPRR2G versus PGLYRP3 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.53.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2G→partner) and Y-score (partner→SPRR2G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	PGLYRP3 →	+1.847	+2.660	<.001	.005	3	8
UPPER_AERODIGESTIVE_TRACT	SPRR4 →	+1.227	+2.402	<.001	.004	2	8
UPPER_AERODIGESTIVE_TRACT	LCE3D →	+2.550	+2.716	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	LCE3E →	+1.646	+2.647	.005	<.001	1	9
SKIN	LCE2C →	+0.248	+0.269	.005	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	SPRR2B →	+0.907	+2.470	.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,497 associations by consensus.

SPRR2G vs PGLYRP3 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →